'It takes two to tango': Bridging the gap between country need and vaccine product innovation.

ABSTRACT:

Background

Despite a growing global commitment to universal health coverage, considerable vaccine coverage and uptake gaps persist in resource-constrained settings. One way of addressing the gaps is by ensuring product innovation is relevant and responsive to the needs of these contexts. Total Systems Effectiveness (TSE) framework has been developed to characterize preferred vaccine attributes from the perspective of country decision-makers to inform research and development (R&D) of products. A proof of concept pilot study took place in Thailand in 2018 to examine the feasibility and usefulness of the TSE approach using a rotavirus hypothetical test-case.

Methods

The excel-based model used multiple-criteria decision analysis (MCDA) to compare and evaluate five hypothetical

SUBMITTER: Archer RA 

PROVIDER: S-EPMC7286512 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature