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A deeper analysis in thyroid research: A meta-epidemiological study of the American Thyroid Association clinical guidelines.


ABSTRACT:

Background

The American Thyroid Association (ATA) uses the GRADE or the American College of Physicians (ACP) system to develop recommendations. Recommendations based on low-quality evidence should spur for the conduction of clinical studies, if feasible. The extent to which recommendations by the ATA based on low-quality of evidence are being actively researched remains unknown.

Methods

Clinical guidelines produced by the ATA using the GRADE or the ACP system to classify evidence were deemed eligible. Reviewers, in duplicate and independently, extracted therapeutic recommendations based on low-quality evidence, whereas recommendations with higher quality of evidence, aimed at diagnosis, or best practice statements were excluded. Eligible recommendations based on low-quality

SUBMITTER: Castillo-Gonzalez DA 

PROVIDER: S-EPMC7286515 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature