Apnea Testing for the Determination of Brain Death: A Systematic Scoping Review.

ABSTRACT: Apnea is one of the three cardinal findings in brain death (BD). Apnea testing (AT) is physiologically and practically complex. We sought to review described modifications of AT, safety and complication rates, monitoring techniques, performance of AT on extracorporeal membrane oxygenation (ECMO), and other relevant considerations regarding AT. We conducted a systematic scoping review to answer these questions by searching the literature on AT in English language available in PubMed or EMBASE since 1980. Pediatric or animal studies were excluded. A total of 87 articles matched our inclusion criteria and were qualitatively synthesized in this review. A large body of the literature on AT since its inception addresses a variety of modifications, monitoring techniques, complication rates, ways

SUBMITTER: Busl KM 

PROVIDER: S-EPMC7286635 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature