Synthesis, biological evaluation and model membrane studies on metal complexes containing aromatic N,O-chelate ligands.

ABSTRACT: Novel lanthanide (Ln) compounds [Ln(L)₂]Cl^.xH₂O (Ln = La³⁺, Ce³⁺, Sm³⁺) containing aromatic N,O-chelate ligands [HL1 = 4-amino-2-(1H-benzimidazol-2-yl)phenol; HL2 = 5-amino-2-(1H-benzimidazol-2-yl)phenol] have been synthesized and structurally characterized by elemental analysis, NMR and IR spectroscopy, molar conductance measurements, and mass spectrometry (MS). The spectroscopic data suggested that the benzimidazolyl-phenol ligands act as N,O-chelate ligands through the iminic nitrogen and phenolic oxygen atoms. Elemental analysis indicated that lanthanide compounds were formed in a 1:2 stoichiometry (metal:ligand). In vitro biological evaluation was carried out using these complexes, exhibiting modera

SUBMITTER: Aragon-Muriel A 

PROVIDER: S-EPMC7286978 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature