Endometrial Immune Profiling: A Method to Design Personalized Care in Assisted Reproductive Medicine.

ABSTRACT: Objective: To assess the efficiency of the endometrial immune profiling as a method to design personalized care to enhance the pregnancy rate in a large heterogeneous infertile population. We hypothesized that some reproductive failures could be induced by a uterine immune dysregulation which could be identified and corrected with a targeted plan. Design: Prospective cohort study. Setting: Multicentric study. Intervention(s) and Main outcome measure(s): One thousand and seven hundred thirty-eight infertile patients had an immune profiling on a timed endometrial biopsy between 2012 and 2018. This test documented the absence or the presence of an endometrial immune dysregulation and identified its type. In case of dysregulation, a targeted personalized plan was su

SUBMITTER: Ledee N 

PROVIDER: S-EPMC7287127 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature