Association of Normal Systolic Blood Pressure Level With Cardiovascular Disease in the Absence of Risk Factors.

ABSTRACT:

Importance

The risk of atherosclerotic cardiovascular disease (ASCVD) at currently defined normal systolic blood pressure (SBP) levels in persons without ASCVD risk factors based on current definitions is not well defined.

Objective

To examine the association of SBP levels with coronary artery calcium and ASCVD in persons without hypertension or other traditional ASCVD risk factors based on current definitions.

Design, setting, and participants

A cohort of 1457 participants free of ASCVD from the Multi-Ethnic Study of Atherosclerosis who were without dyslipidemia (low-density lipoprotein cholesterol level ≥160 mg/dL or high-density lipoprotein cholesterol level <40 mg/dL), diabetes (fasting glucose level ≥126 mg/dL), treatment for hyperlipidemia or diabetes, or curren

SUBMITTER: Whelton SP 

PROVIDER: S-EPMC7287937 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature