Symptom trajectories in the months before and after a suicide attempt in individuals with bipolar disorder: A STEP-BD study.

ABSTRACT:

Objectives

The suicide crisis is a relatively short-lived psychiatric emergency, with transient symptoms that ebb and flow around the suicide attempt. Understanding the dynamic processes of symptoms before and after suicide attempt may aid future prevention efforts.

Methods

Data were drawn from the NIMH STEP-BD study, which followed 4,360 patients with bipolar disorder; a subset attempted suicide during the trial (245/4100 or 5.97% of the sample eligible for analysis). This analysis focused on change in suicidal ideation (SI) in the 120 days before and 120 days after suicide attempt; similar analyses were conducted for other depressive symptoms. Generalized linear mixed models with a two-piece linear function of time corresponding to pre- and post-suicide attempt trends were

SUBMITTER: Ballard ED 

PROVIDER: S-EPMC7289321 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature