Introducing Lu-1, a Novel Lactobacillus jensenii Phage Abundant in the Urogenital Tract.

ABSTRACT: Bacteriophages (phages) play a key role in shaping microbial communities, including those of the human body. Phages are abundant members of the urogenital tract, most often persisting through the lysogenic life cycle as prophages integrated within the genomes of their bacterial hosts. While numerous studies of the urogenital microbiota have focused on the most abundant bacterial member of this niche-Lactobacillus species-very little is known about Lactobacillus phages. Focusing on Lactobacillus jensenii strains from the urinary tract, we identified numerous prophages related to the previously characterized Lv-1 phage from a vaginal L. jensenii strain. Furthermore, we identified a new L. jensenii phage, Lu-1. Evidence suggests that both phages are abundant within the urogenital tract. CRISP

SUBMITTER: Miller-Ensminger T 

PROVIDER: S-EPMC7289420 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature