Impact of Different Sampling Schemes for Decision Making in Soil-Transmitted Helminthiasis Control Programs.

ABSTRACT: Starting and stopping preventive chemotherapy (PC) for soil-transmitted helminthiasis is typically based on the prevalence of infection as measured by Kato-Katz (KK) fecal smears. Kato-Katz-based egg counts can vary highly over repeated stool samples and smears. Consequentially, the sensitivity of KK-based surveys depends on the number of stool samples per person and the number of smears per sample. Given finite resources, collecting multiple samples and/or smears means screening fewer individuals, thereby lowering the statistical precision of prevalence estimates. Using population-level data from various epidemiological settings, we assessed the performance of different sampling schemes executed within the confines of the same budget. We recommend the use of single-slide KK for determinin

SUBMITTER: Coffeng LE 

PROVIDER: S-EPMC7289558 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature