Long-Term Clinical Effects of Carotid Intraplaque Neovascularization in Patients with Coronary Artery Disease.

ABSTRACT:

Objective

To investigate the predictive value of intraplaque neovascularization (IPN) for cardiovascular outcomes.

Materials and methods

We evaluated 217 patients with coronary artery disease (CAD) (158 men; mean age, 68 ± 10 years) with a maximal carotid plaque thickness ≥ 1.5 mm for the presence of IPN using contrast-enhanced ultrasonography. We compared patients with (n = 116) and without (n = 101) IPN during the follow-up period and investigated the predictors of major adverse cardiovascular events (MACE), including cardiac death, myocardial infarction, coronary artery revascularization, and transient ischemic accident/stroke.

Results

During the mean follow-up period of 995 ± 610 days, the MACE rate was 6% (13/217). Patients with IPN had a higher maximal thickness

SUBMITTER: Chung H 

PROVIDER: S-EPMC7289693 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature