Mechanism of Dayuanyin in the treatment of coronavirus disease 2019 based on network pharmacology and molecular docking.

ABSTRACT:

Background

At present, coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2, is spreading all over the world, with disastrous consequences for people of all countries. The traditional Chinese medicine prescription Dayuanyin (DYY), a classic prescription for the treatment of plague, has shown significant effects in the treatment of COVID-19. However, its specific mechanism of action has not yet been clarified. This study aims to explore the mechanism of action of DYY in the treatment of COVID-19 with the hope of providing a theoretical basis for its clinical application.

Methods

First, the TCMSP database was searched to screen the active ingredients and corresponding target genes of the DYY prescription and to further i

SUBMITTER: Ruan X 

PROVIDER: S-EPMC7289712 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature