The Basal Forebrain Modulates Neuronal Response in an Active Olfactory Discrimination Task.

ABSTRACT: Successful completion of sensory decision-making requires focusing on relevant stimuli, adequate signal/noise ratio for stimulus discrimination, and stimulus valence evaluation. Different brain regions are postulated to play a role in these computations; however, evidence suggests that sensory and decision-making circuits are required to interact through a common neuronal pathway to elicit a context-adequate behavioral response. Recently, the basal forebrain (BF) region has emerged as a good candidate, since its heterogeneous projecting neurons innervate most of the cortical mantle and sensory processing circuits modulating different aspects of the sensory decision-making process. Moreover, evidence indicates that the BF plays an important role in attention and in fast modulation of neuron

SUBMITTER: Nunez-Parra A 

PROVIDER: S-EPMC7289987 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature