IMPMD: An Integrated Method for Predicting Potential Associations Between miRNAs and Diseases.

ABSTRACT:

Background

With the rapid development of biological research, microRNAs (miRNAs) have increasingly attracted worldwide attention. The increasing biological studies and scientific experiments have proven that miRNAs are related to the occurrence and development of a large number of key biological processes which cause complex human diseases. Thus, identifying the association between miRNAs and disease is helpful to diagnose the diseases. Although some studies have found considerable associations between miRNAs and diseases, there are still a lot of associations that need to be identified. Experimental methods to uncover miRNA-disease associations are time-consuming and expensive. Therefore, effective computational methods are urgently needed to predict new associations.

Methodolo

SUBMITTER: Wu M 

PROVIDER: S-EPMC7290057 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature