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Clinical characteristics of children with COVID-19: a rapid review and meta-analysis.


ABSTRACT:

Background

Most guidelines on COVID-19 published so far include recommendations for patients regardless of age. Clinicians need a more accurate understanding of the clinical characteristics of children with COVID-19.

Methods

We searched studies reporting clinical characteristics in children with COVID-19 published until March 31, 2020. We screened the literature, extracted the data and evaluated the risk of bias and quality of evidence of the included studies. We combined some of the outcomes (symptoms) in a single-arm meta-analysis using a random-effects model.

Results

Our search retrieved 49 studies, including 25 case reports, 23 case series and one cohort study, with a total of 1,667 patients. Our meta-analysis showed that most children with COVID-19 have mild symp

SUBMITTER: Wang Z 

PROVIDER: S-EPMC7290619 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature