Expression patterns and clinical significances of ENO2 in lung cancer: an analysis based on Oncomine database.

ABSTRACT:

Background

Lung cancer is a heterogeneous malignant tumor involving more than 50 histological subtypes. Currently, molecularly targeted drugs have been shown to have promising applications in the clinical treatment of lung cancer. This study aims to explore the expression patterns and prognostic potential of enolase 2 (ENO2) in lung cancer.

Methods

Differential expressions of ENO2 in lung cancer cases were analyzed using the Oncomine database. Meanwhile, the prognostic potentials of ENO2 in lung cancer were assessed by deploying the Kaplan-Meier plotter database.

Results

Forty-one studies reported a significant difference in ENO2 expression between tumors and the normal healthy control tissues. Among all the studies, there was an upregulation of ENO2 in 29 studies, an

SUBMITTER: Liu D 

PROVIDER: S-EPMC7290642 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature