Scorpion Toxins and Ion Channels: Potential Applications in Cancer Therapy.

ABSTRACT: Apoptosis, a genetically directed process of cell death, has been studied for many years, and the biochemical mechanisms that surround it are well known and described. There are at least three pathways by which apoptosis occurs, and each pathway depends on extra or intracellular processes for activation. Apoptosis is a vital process, but disturbances in proliferation and cell death rates can lead to the development of diseases like cancer. Several compounds, isolated from scorpion venoms, exhibit inhibitory effects on different cancer cells. Indeed, some of these compounds can differentiate between healthy and cancer cells within the same tissue. During the carcinogenic process, morphological, biochemical, and biological changes occur that enable these compounds to modulate cancer but not

SUBMITTER: Duenas-Cuellar RA 

PROVIDER: S-EPMC7290751 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature