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Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt.


ABSTRACT: Astroviruses belong to Astroviridae family which includes two main genera: Mamastroviruses that infect mammals, and Avastroviruses that infect avian hosts. Bats and wild birds are considered among the natural reservoirs for astroviruses. Infections in humans are associated with severe gastroenteritis, especially among children. We conducted surveillance for astroviruses in bats, wild birds, and humans in Egypt. Our results indicated relatively high prevalence of astroviruses in those hosts. Phylogenetic analysis revealed diversity of these viruses within hosts. Detected human viruses showed similarity with classic and variant human astroviruses, as well as similarity with animal-origin viruses. Viruses in bats were dispersed, with similarities to other bat viruses as well as other mammalia

SUBMITTER: El Taweel A 

PROVIDER: S-EPMC7290939 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature