Consciousness and the Dimensionality of DOC Patients via the Generalized Ising Model.

ABSTRACT: The data from patients with severe brain injuries show complex brain functions. Due to the difficulties associated with these complex data, computational modeling is an especially useful tool to examine the structure-function relationship in these populations. By using computational modeling for patients with a disorder of consciousness (DoC), not only we can understand the changes of information transfer, but we also can test changes to different states of consciousness by hypothetically changing the anatomical structure. The generalized Ising model (GIM), which specializes in using structural connectivity to simulate functional connectivity, has been proven to effectively capture the relationship between anatomical structures and the spontaneous fluctuations of healthy controls (HCs). In

SUBMITTER: Abeyasinghe PM 

PROVIDER: S-EPMC7290966 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature