Genome-Wide Patterns of Homozygosity and Relevant Characterizations on the Population Structure in Pietrain Pigs.

ABSTRACT: Investigating the patterns of homozygosity, linkage disequilibrium, effective population size and inbreeding coefficients in livestock contributes to our understanding of the genetic diversity and evolutionary history. Here we used Illumina PorcineSNP50 Bead Chip to identify the runs of homozygosity (ROH) and estimate the linkage disequilibrium (LD) across the whole genome, and then predict the effective population size. In addition, we calculated the inbreeding coefficients based on ROH in 305 Piétrain pigs and compared its effect with the other two types of inbreeding coefficients obtained by different calculation methods. A total of 23,434 ROHs were detected, and the average length of ROH per individual was about 507.27 Mb. There was no regularity on how those runs of homozygosity distr

SUBMITTER: Zhan H 

PROVIDER: S-EPMC7291003 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature