Leftover opioids following adult surgical procedures: a systematic review and meta-analysis.

ABSTRACT:

Background

US opioid prescribing and use escalated over the last two decades, with parallel increases in opioid misuse, opioid-related deaths, and concerns about diversion. Postoperatively prescribed opioids contribute to these problems. Policy makers have addressed this issue by limiting postoperative opioid prescribing. However, until recently, little data existed to guide prescribers on opioid needs postoperatively. This meta-analysis quantitatively integrated the growing literature regarding extent of opioids leftover after surgery and identified factors associated with leftover opioid proportions.

Methods

We conducted a meta-analysis of observational studies quantifying postoperative opioid consumption in North American adults, and evaluated effect size moderators using

SUBMITTER: Schirle L 

PROVIDER: S-EPMC7291535 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature