Exposure to hot and cold environments increases noradrenaline release in the bed nucleus of the stria terminalis in rats.

ABSTRACT:

Aims

Thermoregulatory responses in homeothermic animals, including humans, are classified into involuntary autonomous and voluntary behavioral thermoregulatory responses. Although behavioral thermoregulatory responses are probably driven by positive (pleasant) and/or negative (unpleasant) emotions, the neuronal mechanisms underlying the induction of negative emotions by hot and cold environments remain poorly understood. The bed nucleus of the stria terminalis is a brain region implicated in stress responses and negative emotions, such as fear, anxiety, and aversion. Various stimuli that cause negative emotions, such as immobilization stress, fox odor, gastric distension, and inflammatory pain, increase noradrenaline release in the rat bed nucleus of the stria terminalis, especiall

SUBMITTER: Minami S 

PROVIDER: S-EPMC7292319 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature