Occupational Pesticide Use and Risk of Renal Cell Carcinoma in the Agricultural Health Study.

ABSTRACT:

Background

Agricultural work and occupational pesticide use have been associated with increased risk of renal cell carcinoma (RCC), the most common form of kidney cancer. However, few prospective studies have investigated links to specific pesticides.

Objective

We evaluated the lifetime use of individual pesticides and the incidence of RCC.

Methods

We evaluated the associations between intensity-weighted lifetime days (IWDs) of 38 pesticides and incident RCC in the Agricultural Health Study, a prospective cohort of licensed pesticide applicators in Iowa and North Carolina. Among 55,873 applicators, 308 cases were diagnosed between enrollment (1993-1997) and the end of follow-up (2014-2015). We estimated incidence rate ratios (RRs) and 95% confidence intervals (CIs) us

SUBMITTER: Andreotti G 

PROVIDER: S-EPMC7292387 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature