Problematic internet use: an exploration of associations between cognition and COMT rs4818, rs4680 haplotypes.

ABSTRACT:

Objective

Problematic internet users suffer from impairment in a variety of cognitive domains. Research suggests that COMT haplotypes exert differential effects on cognition. We sought to investigate differences in the genetic profiles of problematic internet users and whether those could shed light on potential cognitive differences.

Methods

We recruited 206 non-treatment seeking participants with heightened impulsive traits and obtained cross-sectional demographic, clinical, and cognitive data as well as the genetic haplotypes of COMT rs4680 and rs4818. We identified 24 participants who presented with problematic internet use (PIU) and compared PIU and non-PIU participants using one-way analysis of variance (ANOVA) and chi square as appropriate.

Results

PIU was asso

SUBMITTER: Ioannidis K 

PROVIDER: S-EPMC7292732 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature