Pregnancy and fertility-related adverse outcomes associated with Chlamydia trachomatis infection: a global systematic review and meta-analysis.

ABSTRACT:

Background

Genital chlamydia infection in women is often asymptomatic, but may result in adverse outcomes before and during pregnancy. The purpose of this study was to examine the strength of the relationships between chlamydia infection and different reproductive health outcomes and to assess the certainty of the evidence.

Methods

This review was registered and followed the Cochrane guidelines. We searched three databases to quantitatively examine adverse outcomes associated with chlamydia infection. We included pregnancy and fertility-related outcomes. We performed meta-analyses on different study designs for various adverse outcomes using unadjusted and adjusted analyses.

Results

We identified 4730 unique citations and included 107 studies reporting 12 pregnancy an

SUBMITTER: Tang W 

PROVIDER: S-EPMC7292777 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature