Molecular Transport across the Ionic Liquid-Aqueous Electrolyte Interface in a MoS₂ Nanopore.

ABSTRACT: Nanopore sequencing of DNA has been enabled by the use of a biological enzyme to thread DNA through an engineered biological nanopore while recording the ionic current flowing through the nanopore. Efforts to realize a similar concept using a solid-state nanopore have been met with several technical challenges, one of which is the high speed of DNA translocation and the other the low ionic current contrast among individual nucleotides. A promising avenue to addressing both problems is using an ionic liquid to slow DNA translocation and a tiny nanopore in the MoS₂ membrane to distinguish individual nucleotides. The physical mechanisms enabling these technical advances have remained elusive. Here, we characterize the ion and DNA transport through the ionic liquid/aqueous electroly

SUBMITTER: Shankla M 

PROVIDER: S-EPMC7292782 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature