Is Hypertension a Real Risk Factor for Poor Prognosis in the COVID-19 Pandemic?

ABSTRACT:

Purpose of review

There is increasing evidence indicating an association between several risk factors and worse prognosis in patients with coronavirus disease 2019 (COVID-19), including older age, hypertension, heart failure, diabetes, and pulmonary disease. Hypertension is of particular interest because it is common in adults and there are concerns related to the use of renin-angiotensin system (RAS) inhibitors in patients with hypertension infected with COVID-19. Levels of angiotensin-converting enzyme 2 (ACE2), a protein that facilitates entry of coronavirus into cells, may increase in patients using RAS inhibitors. Thus, chronic use of RAS inhibition could potentially lead to a more severe and fatal form of COVID-19. In this review, we provide a critical review to the following

SUBMITTER: Drager LF 

PROVIDER: S-EPMC7292934 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature