Quantifying Downstream Healthcare Utilization in Studies of Genomic Testing.

ABSTRACT:

Objectives

The challenges of understanding how interventions influence follow-up medical care are magnified during genomic testing because few patients have received it to date and because the scope of information it provides is complex and often unexpected. We tested a novel strategy for quantifying downstream healthcare utilization after genomic testing to more comprehensively and efficiently identify related services. We also evaluated the effectiveness of different methods for collecting these data.

Methods

We developed a risk-based approach for a trial of newborn genomic sequencing in which we defined primary conditions based on existing diagnoses and family histories of disease and defined secondary conditions based on unexpected findings. We then created patient-speci

SUBMITTER: Mackay ZP 

PROVIDER: S-EPMC7293136 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature