Medications and in-hospital outcomes in infants born at 22-24 weeks of gestation.

ABSTRACT:

Objective

To evaluate the most commonly used medications and in-hospital morbidities and mortality in infants born 22-24 weeks of gestation.

Study design

Multicenter retrospective cohort study of infants born 22-24 weeks of gestation (2006-2016), without major congenital anomalies and with available medication data obtained from neonatal intensive care units managed by the Pediatrix Medical Group.

Results

This study included 7578 infants from 195 sites. Median (25th, 75th percentile): birthweight was 610 g (540, 680); the number of distinct medications used was 13 (8, 18); and different antimicrobial exposure was 4 (2, 5). The most common morbidities were BPD (41%) and grade III or IV IVH (20%), and overall survival varied from 46% (2006) to 57% (2016).

Conclusions

SUBMITTER: Puia-Dumitrescu M 

PROVIDER: S-EPMC7293630 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature