Outcomes for Surgery in Large Cell Lung Neuroendocrine Cancer.

ABSTRACT: INTRODUCTION:There are limited small, single-institution observational studies examining the role of surgery in large cell neuroendocrine cancer (LCNEC). We investigated the outcomes of surgery for stage I to IIIA LCNEC by using the National Cancer Database. METHODS:Patients with stage I to IIIA LCNEC were identified in the National Cancer Database (2004-2015) and grouped by treatment: definitive chemoradiation versus surgery. Overall survival, by stage, was the primary outcome. Outcomes of surgical patients were also compared with those of patients with SCLC or other non-small cell histotypes. RESULTS:A total of 6092 patients met the criteria: 96%, 94%, 75%, and 62% of patients received an operation for stage I, II, IIIA, and cN2 disease, respectively. Complete resection was achieved in a

SUBMITTER: Raman V 

PROVIDER: S-EPMC7293864 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature