Cold Blooded: Evaluating Brain Temperature by MRI During Surface Cooling of Human Subjects.

ABSTRACT:

Background

Targeted temperature management (TTM) confers neurological and survival benefits for post-cardiac arrest patients with return of spontaneous circulation (ROSC) who remain comatose. Specialized equipment for induction of hypothermia is not available in the prehospital setting, and there are no reliable methods for emergency medical services personnel to initiate TTM. We hypothesized that the application of surface cooling elements to the neck will decrease brain temperature and act as initiators of TTM.

Methods

Magnetic resonance (MR) spectroscopy was used to evaluate the effect of a carotid surface cooling element on brain temperature in healthy adults.

Results

Six individuals completed this study. We measured a temperature drop of 0.69 ± 0.38 °C (95% CI) i

SUBMITTER: Curran EJ 

PROVIDER: S-EPMC7293900 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature