Aneurysm characteristics, coil packing, and post-coiling hemodynamics affect long-term treatment outcome.

ABSTRACT:

Background

Recurrence of intracranial aneurysms after endovascular coiling is a serious clinical concern.

Objective

We hypothesized that recurrence is associated with aneurysm morphology and flow, as well as the coil intervention and the induced flow modifications.

Methods

We collected 52 primary-coiling aneurysm cases that were either occluded (n=34) or recurrent (n=18) at >1 year follow-up. We created aneurysm models from pre-coiling digital subtraction angiographic images, calculated aneurysm morphology, simulated pre-coiling hemodynamics, modeled coil deployment, and obtained post-coiling hemodynamics for each case. We performed univariable analysis on 26 morphologic, treatment-specific, and hemodynamic parameters to distinguish between recurrent and occluded grou

SUBMITTER: Damiano RJ 

PROVIDER: S-EPMC7293941 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature