Effects and cost of different strategies to eliminate hepatitis C virus transmission in Pakistan: a modelling analysis.

ABSTRACT:

Background

The WHO elimination strategy for hepatitis C virus advocates scaling up screening and treatment to reduce global hepatitis C incidence by 80% by 2030, but little is known about how this reduction could be achieved and the costs of doing so. We aimed to evaluate the effects and cost of different strategies to scale up screening and treatment of hepatitis C in Pakistan and determine what is required to meet WHO elimination targets for incidence.

Methods

We adapted a previous model of hepatitis C virus transmission, treatment, and disease progression for Pakistan, calibrating using available data to incorporate a detailed cascade of care for hepatitis C with cost data on diagnostics and hepatitis C treatment. We modelled the effect on various outcomes and costs of al

SUBMITTER: Lim AG 

PROVIDER: S-EPMC7295205 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature