Associations of accelerometer-measured physical activity and sedentary time with chronic kidney disease: The Framingham Heart Study.

ABSTRACT:

Background

Few studies examined the individual and conjoint associations of accelerometer-measured physical activity (PA) and sedentary times with the prevalence of chronic kidney disease (CKD) among older adults.

Methods

We evaluated 1,268 Framingham Offspring Study participants (mean age 69.2 years, 53.8% women) between 2011 and 2014. CKD was defined as an estimated glomerular filtration rate (eGFR) <60 ml/min/1.732 and/or urine albumin-to-creatinine ratio (UACR) ≥25/35 μg/mg (men/women). We used multivariable logistic regression models to relate time spent being sedentary and active with the odds of CKD. We then performed compositional data analysis to estimate the change in the eGFR and UACR when a fixed proportion of time in one activity behavior (among the following: m

SUBMITTER: Lee J 

PROVIDER: S-EPMC7295223 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature