Neurocognitive impairment after neonatal sepsis: protocol for a systematic review and meta-analysis.

ABSTRACT:

Introduction

The effect of neonatal sepsis on the developing brain is not well documented. We aim to perform evidence synthesis to determine the outcome of neurodevelopmental impairment and intellectual disability among survivors of neonatal sepsis. The data gathered will inform on the long-term neurocognitive outcomes of neonates with sepsis and the measures used to document their developmental disability.

Methods and analysis

We will perform a search based on the following parameters: neonates and infants less than 90 days old diagnosed with sepsis who had neurocognitive outcomes or measures of developmental disability reported. We will search PubMed, Cochrane Central, Embase and Web of Science for articles in English language published between January 2010 and December 20

SUBMITTER: Pek JH 

PROVIDER: S-EPMC7295426 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature