High muscle-to-fat ratio is associated with lower risk of chronic kidney disease development.

ABSTRACT:

Background

Obesity, a known risk factor for chronic kidney disease (CKD), is generally assessed using body mass index (BMI). However, BMI may not effectively reflect body composition, and the impact of muscle-to-fat (MF) mass balance on kidney function has not been elucidated. This study evaluated the association between body muscle and fat mass balance, represented as the MF ratio, and incident CKD development.

Methods

Data were retrieved from a prospective community-based cohort study (Korean Genome and Epidemiology Study). Muscle and fat mass were measured using multifrequency bioelectrical impedance analysis. The study endpoint was incident CKD (estimated glomerular filtration rate <60 mL/min/1.73 m² in at least two or more consecutive measurements during the

SUBMITTER: Jhee JH 

PROVIDER: S-EPMC7296269 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature