Analysis of Normal High-Frequency Intracranial Pressure Values and Treatment Threshold in Neurocritical Care Patients: Insights into Normal Values and a Potential Treatment Threshold.

ABSTRACT:

Importance

Intracranial pressure (ICP) elevation is a compartment syndrome that impairs blood flow to the brain. Despite the importance of ICP values in neurocritical care, normal ICP values and the precise ICP threshold at which treatment should be initiated remain uncertain.

Objective

To refine our understanding of normal ICP values and determine the ICP threshold most strongly associated with outcome.

Design, setting, and participants

Prospective observational study (2004-2010), with outcomes determined at hospital discharge. The study included neurocritical care patients from a single level I trauma center, San Francisco General Hospital. Three hundred eighty-three patients had a traumatic brain injury with or without craniectomy; 140 patients had another indicati

SUBMITTER: Hawryluk GWJ 

PROVIDER: S-EPMC7296460 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature