White-coat hypertension and incident end-stage renal disease in patients with non-dialysis chronic kidney disease: results from the C-STRIDE Study.

ABSTRACT:

Background

Controversy remains whether white coat hypertension (WCH) is associated with renal prognosis in patients with chronic kidney disease (CKD).

Methods

In the present multicenter, prospective study, we analyzed data of participants with CKD stage 1-4 from the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE). WCH was defined according to two criteria as follows: A, clinical blood pressure (BP) ≥ 140/90 mm Hg and average 24-h ambulatory BP < 130/80 mm Hg; B, clinical BP ≥ 130/80 mm Hg and daytime ambulatory BP < 130/80 mm Hg. Renal outcome was defined as initiation of renal replacement therapy. The association of WCH with renal events was evaluated by Cox regression model.

Results

A total of 1714 patients with CKD were included in the present analysis. T

SUBMITTER: Wang Q 

PROVIDER: S-EPMC7296682 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature