3D genome architecture coordinates trans and cis regulation of differentially expressed ear and tassel genes in maize.

ABSTRACT:

Background

Maize ears and tassels are two separate types of inflorescence which are initiated by similar developmental processes but gradually develop distinct architectures. However, coordinated trans and cis regulation of differentially expressed genes determining ear and tassel architecture within the 3D genome context is largely unknown.

Results

We identify 56,055 and 52,633 open chromatin regions (OCRs) in developing maize ear and tassel primordia using ATAC-seq and characterize combinatorial epigenome features around these OCRs using ChIP-seq, Bisulfite-seq, and RNA-seq datasets. Our integrative analysis of coordinated epigenetic modification and transcription factor binding to OCRs highlights the cis and trans regulation of differentially expressed genes in ear and ta

SUBMITTER: Sun Y 

PROVIDER: S-EPMC7296987 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature