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Auditory event-related potentials and associations with sensory patterns in children with autism spectrum disorder, developmental delay, and typical development.


ABSTRACT: Atypical sensory response patterns are common in children with autism and developmental delay. Expanding on previous work, this observational electroencephalogram study assessed auditory event-related potentials and their associations with clinically evaluated sensory response patterns in children with autism spectrum disorder (n = 28), developmental delay (n = 17), and typical development (n = 39). Attention-orienting P3a responses were attenuated in autism spectrum disorder relative to both developmental delay and typical development, but early sensory N2 responses were attenuated in both autism spectrum disorder and developmental delay relative to typical development. Attenuated event-related potentials involving N2 or P3a components, or a P1 × N2 interaction, were

SUBMITTER: Donkers FC 

PROVIDER: S-EPMC7297652 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature