Male breast cancer: clinicopathological characterization of a National Danish cohort 1980-2009.

ABSTRACT:

Background

To describe relevant pathological parameters of Danish male breast cancer patients (MBCP) diagnosed from 1980 to 2009, and to relate these data to treatment, overall survival (OS) and standardized mortality rate (SMR).

Materials and methods

The MBCP cohort was defined from national Danish registers. A total of 643 MBCP were identified with tissue available in 457. Among these, 384 were primary operable. Where tissue blocks were available, tumor type, grade, estrogen receptor (ER), progesteron receptor (PgR) and androgen-receptor (AR) status as well as HER 2 and Ki67 were performed. OS was quantified by Kaplan-Meier estimates and SMR was calculated based on mortality rate among patients relative to the mortality rate in the general population.

Results

Male b

SUBMITTER: Jylling AMB 

PROVIDER: S-EPMC7297815 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature