Sensory profiles in women with neuropathic pain after breast cancer surgery.

ABSTRACT:

Purpose

We performed a detailed analysis of sensory function in patients with chronic post-surgical neuropathic pain (NP) after breast cancer treatments by quantitative sensory testing (QST) with DFNS (German Research Network on Neuropathic Pain) protocol and bed side examination (BE). The nature of sensory changes in peripheral NP may reflect distinct pathophysiological backgrounds that can guide the treatment choices. NP with sensory gain (i.e., hyperesthesia, hyperalgesia, allodynia) has been shown to respond to Na⁺-channel blockers (e.g., oxcarbazepine).

Methods

104 patients with at least "probable" NP in the surgical area were included. All patients had been treated for breast cancer 4-9 years ago and the handling of the intercostobrachial nerve (ICBN) was ve

SUBMITTER: Mustonen L 

PROVIDER: S-EPMC7297844 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature