Associations between different dimensions of prenatal distress, neonatal hippocampal connectivity, and infant memory.

ABSTRACT: Prenatal maternal distress-an umbrella concept encompassing multiple negative psychological states including stress, anxiety, and depression-is a substantial prenatal exposure. Consistent across preclinical and human studies, the hippocampus displays alterations due to prenatal distress. Nevertheless, most prenatal distress studies do not focus on multiple dimensions of, have not examined hippocampal functional connectivity in association with, and do not consider observer-based functional outcomes related to distress. We investigated the effects of different dimensions of prenatal distress in pregnant adolescents, a population at high risk for distress, in association with neonatal hippocampal connectivity and infant memory. In pregnant adolescents (n = 42), we collected four measures of

SUBMITTER: Scheinost D 

PROVIDER: S-EPMC7297970 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature