Age-Related Changes in the Neural Processes of Reward-Directed Action and Inhibition of Action.

ABSTRACT: Aging is associated with structural and functional brain changes which may impact the regulation of motivated behaviors, including both action and inhibition of action. As behavioral regulation is often exercised in response to reward, it remains unclear how aging may influence reward-directed action and inhibition of action differently. Here we addressed this issue with the functional magnetic resonance imaging data of 72 participants (aged 21-74) performing a reward go/no-go (GNG) task with approximately 2/3 go and 1/3 no-go trials. The go and no-go success trials were rewarded with a dollar or a nickel, and the incorrect responses were penalized. An additional block of the GNG task without reward/punishment served as the control to account for age-related slowing in processing speed. Th

SUBMITTER: Le TM 

PROVIDER: S-EPMC7298110 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature