The impact of vitamin D food fortification and health outcomes in children: a systematic review and meta-regression.

ABSTRACT:

Objective

Vitamin D (vitD) deficiency is a global childhood health problem. Food fortification is a promising strategy to curb vitD deficiency. We aimed to assess the effectiveness of utilizing vitD fortification in staple foods to improve 25hydroxyvitamin D (25(OH)D) concentration and to reduce the prevalence of vitD deficiency among healthy children.

Methods

We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) evaluating the use of vitD fortified food products compared to no fortification among healthy children aged 1-18 years old. We searched Medline, Embase, Global Health, and Cochrane (CENTRAL) databases from database inception until May 2019. Independently, six reviewers in pairs screened titles and abstracts, assessed the full text

SUBMITTER: Al Khalifah R 

PROVIDER: S-EPMC7298752 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature