Detection of DNA of filariae closely related to Mansonella perstans in faecal samples from wild non-human primates from Cameroon and Gabon.

ABSTRACT:

Background

The Onchocercidae is a family of filarial nematodes with several species of medical or veterinary importance. Microfilariae are found in the blood and/or the dermis and are usually diagnosed in humans by microscopy examination of a blood sample or skin biopsy. The main objectives of this study were to evaluate whether filariae DNA can be detected in faecal samples of wild non-human primates (NHPs), whether the detected parasites were closely related to those infecting humans and whether filarial DNA detection in faeces is associated with co-infections with nematodes (Oesophagostumum sp. and Necator sp.) known to cause blood loss while feeding on the host intestinal mucosa.

Methods

A total of 315 faecal samples from 6 species of NHPs from Cameroon and Gabon were an

SUBMITTER: Gaillard CM 

PROVIDER: S-EPMC7298833 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature