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The impact of adjuvant surgical treatment of nontuberculous mycobacterial pulmonary disease on prognosis and outcome.


ABSTRACT:

Background

Lung resection in patients with nontuberculous mycobacterial pulmonary disease (NTM-PD) has been reported to be associated with favorable outcomes. However, little is known regarding the risk and prognostic factors for refractory and recurrent cases. We aimed to evaluate the overall impact and benefit of adjuvant lung surgery by comparing NTM-PD patients who underwent adjuvant lung resection with those treated exclusively with antibiotics. We also investigated the efficacy of serum IgA antibody against glycopeptidolipid (GPL) core antigen (GPL core antibody) to monitor disease activity and predict the recurrence of disease after adjuvant lung resection.

Methods

We retrospectively evaluated the clinical characteristics and surgical outcomes of 35 patients surgicall

SUBMITTER: Fukushima K 

PROVIDER: S-EPMC7298848 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature