Relationship between caffeine intake and infertility: a systematic review of controlled clinical studies.

ABSTRACT:

Background

For a long time, the relationship between caffeine consumption and infertility in the general population is unclear, this study is aimed to systematically review the evidence from any type of controlled clinical studies to explore whether caffeine intake is a risk factor for human infertility.

Methods

Seven databases were searched from inception to May 2019. We included women/men without a history of infertility but were willing to have children in prospective studies and women/men who were diagnosed with infertility in retrospective studies. The observed exposure factor should be caffeine or caffeine containing beverage. Diagnosis of infertility or not for participants was the key outcome. The Newcastle-Ottawa scale (NOS) or Cochrane risk of bias tool were used t

SUBMITTER: Bu FL 

PROVIDER: S-EPMC7298863 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature