Interplay between Selenium, selenoprotein genes, and oxidative stress in honey bee Apis mellifera L.

ABSTRACT: The honey bee, Apis mellifera L., is a major pollinator insect that lacks novel "selenoprotein genes", rendering it susceptible to elevated levels of Selenium (Se) occurring naturally in the environment. We investigated the effects of two inorganic forms of Se on biological traits, oxidative stress, and gene regulation. Using bioassay arenas in the laboratory, one-day old sister bees were fed ad libitum 4 different concentrations of selenate and selenite, two common inorganic forms of Se. The transcription levels of 4 honey bee antioxidant genes were evaluated, and three putative selenoprotein-like genes (SELENOT, SELENOK, SELENOF) were characterized as well as Sbp2, a Selenium binding protein required for the translation of selenoproteins mRNA. Oxidative stress and Se residues were subseq

SUBMITTER: Alburaki M 

PROVIDER: S-EPMC7298915 | biostudies-literature | 2019 Aug - Sep

REPOSITORIES: biostudies-literature