Opposite effect of ablation on early/late-phase thromboembolic incidence in patients with atrial fibrillation: A meta-analysis on more than 100 000 individuals.

ABSTRACT:

Background

Atrial fibrillation (AF) is an important risk factor for thromboembolic events, for which catheter ablation represents an effective therapy for rhythm control. Intuitively, ablation may reduce the incidence of thromboembolism, but data is quite limited.

Hypothesis

Catheter ablation was associated with the fewer risk of thromboembolism compared with nonablation in patients with AF.

Methods

A systematic search was performed in PubMed, EMBASE, the Web of Science, and the Cochrane Library from inception to September 2019. Random-effects model was used to estimate the risk ratios (RR) for the thromboembolic events between the ablation and nonablation groups.

Results

Twenty-five studies (12 randomized controlled trials and 13 observational studies) with 10

SUBMITTER: Liu M 

PROVIDER: S-EPMC7298999 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature