Oxidative status of maternal blood in pregnancies burdened by inherited thrombophilias.

ABSTRACT: Oxidative status of maternal blood represents an important parameter of pregnancy that is involved in both, regulation of physiological processes and (if significantly altered) development of different pregnancy complications. Inherited thrombophilias represent genetic disorders that increase the risk of thromboembolism in pregnancy. Little is known about the impact of thrombophilia on the oxidative status of maternal blood. In this study, we analyzed oxidative status of blood of 56 women with pregnancies burdened by inherited thrombophilias. The status was established at three different trimesters using biochemical assays and electrochemical measurements, and it was compared to 10 age- and trimester-matching controls. Activities of superoxide dismutase, catalase, and glutathione reductase

SUBMITTER: Bogdanovic Pristov J 

PROVIDER: S-EPMC7299371 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature